Moracin P ( —— )

产品货号. M31251 CAS No. 102841-46-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Moracin P
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.
产品描述

Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.
体外实验

Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC50 values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner.
体内实验

——
同义词

——
通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

计算器

产品手册

关联产品

UC-1728

UC-1728 是一种有效的兔可溶性环氧化物水解酶抑制剂（对兔肝脏的IC50：2 nM）。通过皮下注射 sEH 抑制剂（UC1728，3 mg/kg）或载体对照（PEG400）对兔子进行治疗，并使用改良的 Hackett-McDonald 评分系统在前房内 LPS 注射后 6、24 和 48 小时评估葡萄膜炎。
blestriarene C

Cirrhopetalanthrin (Blestriarene C) is a natural product.
Cephalosporin C zinc...

头孢菌素 C 锌盐是 SAMHD1 的有效抑制剂（IC50：1.1 ± 0.1 μM），这种抑制很大程度上归因于锌的存在。